منابع مشابه
Chronic plaque psoriasis.
Chronic plaque psoriasis, the most common form of psoriasis, is a papulosquamous disease defined by erythematous plaques with a silvery scale. The diagnosis usually is clinical, but occasionally a biopsy is necessary. Psoriasis affects 0.6 to 4.8 percent of the U.S. population, and about 30 percent of affected patients have a first-degree relative with the disease. Psoriasis is a T-cell-mediate...
متن کاملTreating pediatric plaque psoriasis: challenges and solutions
Psoriasis is a T-lymphocyte-mediated chronic inflammatory disorder involving the skin and joints. Nearly 3.5% of the population has been diagnosed to have psoriasis. In a dermatology department, almost one-third of psoriasis patients are in the pediatric age group. With an annual prevalence of up to 0.71%, childhood psoriasis can now be regarded as a frequently seen chronic inflammatory skin di...
متن کاملThe role of Staphylococcus superantigens in chronic plaque type psoriasis
Background: T cell activation is discussed as an important factor in the pathogenesis of psoriasis. Recently, a lot of attention has been paid to the role of superantigens in T cell activation in the pathogenesis of psoriasis. In this study, the role of staphylococcal superantigens in the pathogenesis of psoriasis with identification of staphylococcal toxin levels in the skin lesions of p...
متن کاملEtanercept in the treatment of plaque psoriasis
Etanercept is approved for the treatment of moderate to severe plaque psoriasis at a dose of 50 mg twice weekly for 3 months followed by a maintenance dosage of 50 mg weekly thereafter. Clinical studies have shown excellent efficacy, favorable benefit to side-effects ratio, and safe long-term usage. Extensive information on safety is available as etanercept has been used for many years for othe...
متن کاملManagement of Moderate to Severe Plaque Psoriasis
cancer, arthritis, hypertension, heart disease, diabetes, and depression (Rapp 1999). In the last decade, a new understanding about the pathophysiology of psoriasis has resulted in the development of a new class of agents for these patients: targeted biologic therapy. These novel treatments target specific immunologic processes involved in the genesis of this disease, providing significant clin...
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ژورنال
عنوان ژورنال: Dermatologie pro praxi
سال: 2019
ISSN: 1802-2960,1803-5337
DOI: 10.36290/der.2019.022